GHK-Cu (Copper Peptide)

50mg

GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine, a tripeptide that occurs naturally in plasma and binds copper with high affinity. It is studied in dermal fibroblast cultures for collagen, elastin and glycosaminoglycan synthesis, in animal wound models for matrix remodeling, and in gene expression profiling studies. Hair follicle and copper transport models round out the literature.

• Extracellular matrix synthesis
• Dermal fibroblast signaling
• Copper transport
• Gene expression profiling

Models: Dermal fibroblast cultures; animal wound models; skin explants

BPC-157

10mg

BPC-157 is a stable 15 amino acid pentadecapeptide derived from a protective protein found in gastric juice. It is studied in rodent models of tendon, ligament, muscle and gastrointestinal mucosa injury, and in tendon fibroblast cultures for cell outgrowth and migration. Mechanistic work focuses on VEGFR2 and nitric oxide system signaling, angiogenesis and growth hormone receptor expression.

• Tendon, ligament and muscle injury models
• Angiogenesis and VEGFR2 signaling
• Nitric oxide system
• GI mucosal models

Models: Rodent injury models; tendon fibroblast cultures

TB-500 / Thymosin Beta-4

10mg

TB-500 is the research name for synthetic thymosin beta-4, a 43 amino acid actin-sequestering peptide present in most cell types. It is studied for cell migration, angiogenesis and tissue remodeling in rodent dermal wound models, in cardiac injury models in mice and in corneal epithelial cultures. Its central LKKTET actin-binding motif is the subject of fragment studies.

• Actin sequestration and cell migration
• Dermal wound models
• Cardiac and corneal injury models
• Angiogenesis

Models: Rodent wound and cardiac models; corneal epithelial cultures